SS-31
Mitochondria-Targeting Peptide
- Form
- Lyophilized powder
- Storage
- -20°C (lyophilized)
- Origin
- USA lab
from$139
SS-31 is a synthetic mitochondria-targeting tetrapeptide reference material used in laboratory investigations of cardiolipin-stabilization and mitochondrial-function signaling.
- Cardiolipin-stabilization research
- Mitochondrial-function pathway models
- In-vitro cellular-energy studies
SKU: AP-SS31-10MG
3 vial minimum per order — mix any products
Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Reconstitution ReferenceOptional — how strong is the mixed vial?
Mixing a powder vial with water? Fill in the fields — results update as you type.
Mixing 10 mg of peptide into 2 mL of water makes a 5 mg/mL solution. Each 0.1 mL contains 0.5 mg.
Reference for in-vitro laboratory handling only. Outputs describe the physical properties of the reconstituted vial (concentration and mass drawn) — they are not dosing guidance, administration instructions, or medical advice. Verify all measurements independently.
The science behind SS-31
A structured overview of the published literature surrounding SS-31 (Elamipretide) as a mitochondria-targeting research peptide.
SS-31 (Elamipretide) is a synthetic mitochondria-targeting tetrapeptide that concentrates in the inner mitochondrial membrane and interacts with the phospholipid cardiolipin. It is studied as a reference material for mitochondrial-function research.
The peptide is prominent in mitochondrial-medicine literature, used as a tool to probe cardiolipin-associated bioenergetics.
The material supplied here is a laboratory reference standard, and the summaries below describe only findings reported in published research.
SS-31 belongs to the Szeto-Schiller (SS) peptide family, developed from research into cell-permeable, mitochondria-targeting antioxidant peptides.
The literature is predominantly preclinical and in-vitro, examining cardiolipin interaction and mitochondrial bioenergetics, alongside clinical research in mitochondrial disorders.
The central mechanism studied is selective binding to cardiolipin in the inner mitochondrial membrane, reported to stabilize cristae architecture and improve electron-transport efficiency in models of mitochondrial dysfunction.
Investigators also examine reported reductions in reactive-oxygen-species production in mitochondrial models — mechanistic laboratory observations.
Cardiolipin interaction
Referenced in studies of inner-membrane phospholipid binding.
Mitochondrial bioenergetics
Examined in electron-transport and ATP-production models.
Oxidative-stress research
Studied for reported effects on mitochondrial ROS.
Cellular-energy systems
Explored in preclinical models of mitochondrial dysfunction.
What is SS-31?
A synthetic mitochondria-targeting tetrapeptide (Elamipretide) supplied as a laboratory reference material for mitochondrial-function research.
What kind of research references SS-31?
Preclinical and in-vitro studies of cardiolipin interaction and mitochondrial bioenergetics.
Is SS-31 approved for human or veterinary use?
No. SS-31 is not approved by the FDA or any regulatory authority for human or animal use. It is sold exclusively for in-vitro and laboratory research and is not for consumption.
How is the reference material characterized?
Each released lot is supplied as a lyophilized powder with a lot-specific certificate of analysis reporting HPLC purity of ≥ 99%. The certificate is tied to the specific released lot.
How should the compound be stored?
Lyophilized material is typically stored at -20°C, protected from light and moisture. Handling should follow standard laboratory practice for peptide reference materials. We do not provide reconstitution, dosing, or administration guidance.
- Szeto HH. First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. Br J Pharmacol (2014).
- Birk AV, et al. The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria. J Am Soc Nephrol (2013).
Links open a curated peer-reviewed search on PubMed. Allpointe Bio Research is not affiliated with the cited authors or publishers.
Research-Use Statement
The information above is provided for educational and scientific-reference purposes only and summarizes findings reported in the published preclinical and in-vitro literature. It is not medical advice and does not describe outcomes, benefits, or applications for humans or animals. SS-31 is supplied strictly as a laboratory reference material for in-vitro and research use only — it is not a drug or supplement, is not approved for human or veterinary use, and is not for consumption. Allpointe Bio Research does not provide clinical, dosing, reconstitution, or administration guidance.