MOTS-C
Mitochondrial-Derived Peptide
- Form
- Lyophilized powder
- Storage
- -20°C (lyophilized)
- Origin
- USA lab
$99
MOTS-C is a synthetic mitochondrial-derived peptide reference material used in laboratory investigations of mitochondrial signaling and metabolic-regulation research.
- Mitochondrial-signaling research
- Metabolic-regulation pathway models
- In-vitro exercise-mimetic studies
SKU: AP-MOTSC-10MG
3 vial minimum per order — mix any products
Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Reconstitution ReferenceOptional — how strong is the mixed vial?
Mixing a powder vial with water? Fill in the fields — results update as you type.
Mixing 10 mg of peptide into 2 mL of water makes a 5 mg/mL solution. Each 0.1 mL contains 0.5 mg.
Reference for in-vitro laboratory handling only. Outputs describe the physical properties of the reconstituted vial (concentration and mass drawn) — they are not dosing guidance, administration instructions, or medical advice. Verify all measurements independently.
The science behind MOTS-C
A structured overview of the published literature surrounding MOTS-C as a mitochondrial-derived signaling peptide.
MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. It is studied as a reference material for metabolic- and mitochondrial-signaling research.
As a prominent member of the mitochondrial-derived peptide family, MOTS-C is widely referenced in metabolic-regulation and exercise-mimetic literature.
The material supplied here is a laboratory reference standard, and the summaries below describe only findings reported in published research.
MOTS-C was identified through research into small open-reading frames within mitochondrial DNA, revealing a peptide with reported roles in cellular metabolism.
The literature is predominantly preclinical and in-vitro, examining metabolic regulation and stress-response signaling. Human clinical evidence remains limited.
The most-discussed mechanism involves modulation of the AMPK metabolic-signaling pathway and folate–methionine metabolism, reported in cellular and rodent models.
MOTS-C has also been reported to translocate to the nucleus under metabolic stress and influence stress-adaptive gene expression — exploratory laboratory observations.
Mitochondrial signaling
Referenced in studies of mitochondrial-derived peptide biology.
Metabolic regulation
Examined in AMPK- and glucose-metabolism models.
Exercise-mimetic research
Studied in preclinical models of metabolic adaptation.
Aging-metabolism systems
Explored in models of metabolic decline with age.
What is MOTS-C?
A 16-amino-acid mitochondrial-derived peptide supplied as a laboratory reference material for metabolic-signaling research.
What kind of research references MOTS-C?
Preclinical and in-vitro studies of AMPK signaling and metabolic regulation. Human evidence remains limited.
Is MOTS-C approved for human or veterinary use?
No. MOTS-C is not approved by the FDA or any regulatory authority for human or animal use. It is sold exclusively for in-vitro and laboratory research and is not for consumption.
How is the reference material characterized?
Each released lot is supplied as a lyophilized powder with a lot-specific certificate of analysis reporting HPLC purity of ≥ 99%. The certificate is tied to the specific released lot.
How should the compound be stored?
Lyophilized material is typically stored at -20°C, protected from light and moisture. Handling should follow standard laboratory practice for peptide reference materials. We do not provide reconstitution, dosing, or administration guidance.
- Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis. Cell Metab (2015).
- Reynolds JC, et al. MOTS-c and metabolic stress adaptation. (review).
Links open a curated peer-reviewed search on PubMed. Allpointe Bio Research is not affiliated with the cited authors or publishers.
Research-Use Statement
The information above is provided for educational and scientific-reference purposes only and summarizes findings reported in the published preclinical and in-vitro literature. It is not medical advice and does not describe outcomes, benefits, or applications for humans or animals. MOTS-C is supplied strictly as a laboratory reference material for in-vitro and research use only — it is not a drug or supplement, is not approved for human or veterinary use, and is not for consumption. Allpointe Bio Research does not provide clinical, dosing, reconstitution, or administration guidance.