Semax
Synthetic Neuropeptide
- Form
- Lyophilized powder
- Storage
- -20°C (lyophilized)
- Origin
- USA lab
from$59
Semax is a synthetic peptide reference material used in laboratory investigations of BDNF-related signaling and neuroprotection research.
- BDNF-signaling research
- Neuroprotection pathway models
- In-vitro cognition-signaling studies
SKU: AP-SEMAX-5MG
3 vial minimum per order — mix any products
Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Reconstitution ReferenceOptional — how strong is the mixed vial?
Mixing a powder vial with water? Fill in the fields — results update as you type.
Mixing 5 mg of peptide into 2 mL of water makes a 2.5 mg/mL solution. Each 0.1 mL contains 0.25 mg.
Reference for in-vitro laboratory handling only. Outputs describe the physical properties of the reconstituted vial (concentration and mass drawn) — they are not dosing guidance, administration instructions, or medical advice. Verify all measurements independently.
The science behind Semax
A structured overview of the published literature surrounding Semax as a synthetic neuropeptide research compound.
Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4-10) with a stabilizing C-terminal extension. It is studied as a reference material for BDNF- and neuroprotection-signaling research.
The peptide is referenced in preclinical neuropharmacology literature examining cognition and neuroprotection.
The material supplied here is a laboratory reference standard, and the summaries below describe only findings reported in published research.
Semax was synthesized from the ACTH(4-10) fragment with a C-terminal Pro-Gly-Pro extension to resist enzymatic degradation, developed within Russian neuropeptide research programs.
The literature is predominantly preclinical and rodent-based, examining neuroprotection and cognition signaling. Independent replication and human evidence remain limited.
The most-discussed mechanism is reported upregulation of brain-derived neurotrophic factor (BDNF) and its receptor TrkB in preclinical models.
Semax has also been examined for reported effects on the dopaminergic and serotonergic systems and on enkephalin degradation — exploratory laboratory observations.
BDNF-signaling models
Referenced in studies of BDNF/TrkB expression in vitro and in rodents.
Neuroprotection research
Examined in preclinical ischemia and neuroprotection models.
Cognition signaling
Studied in rodent learning- and memory-signaling systems.
Neurotransmitter systems
Explored in dopaminergic and serotonergic models.
What is Semax?
A synthetic heptapeptide (ACTH 4-10 analog) supplied as a laboratory reference material for BDNF- and neuroprotection-signaling research.
What kind of research references Semax?
Predominantly preclinical rodent models of neuroprotection and cognition signaling; human evidence remains limited.
Is Semax approved for human or veterinary use?
No. Semax is not approved by the FDA or any regulatory authority for human or animal use. It is sold exclusively for in-vitro and laboratory research and is not for consumption.
How is the reference material characterized?
Each released lot is supplied as a lyophilized powder with a lot-specific certificate of analysis reporting HPLC purity of ≥ 99%. The certificate is tied to the specific released lot.
How should the compound be stored?
Lyophilized material is typically stored at -20°C, protected from light and moisture. Handling should follow standard laboratory practice for peptide reference materials. We do not provide reconstitution, dosing, or administration guidance.
- Dolotov OV, et al. Semax, an ACTH(4-10) analogue, regulates BDNF expression in the rat brain. J Neurochem (2006).
- Semax neuroprotection literature (review).
Links open a curated peer-reviewed search on PubMed. Allpointe Bio Research is not affiliated with the cited authors or publishers.
Research-Use Statement
The information above is provided for educational and scientific-reference purposes only and summarizes findings reported in the published preclinical and in-vitro literature. It is not medical advice and does not describe outcomes, benefits, or applications for humans or animals. Semax is supplied strictly as a laboratory reference material for in-vitro and research use only — it is not a drug or supplement, is not approved for human or veterinary use, and is not for consumption. Allpointe Bio Research does not provide clinical, dosing, reconstitution, or administration guidance.