PT-141
Melanocortin Receptor Agonist
- Form
- Lyophilized powder
- Storage
- -20°C (lyophilized)
- Origin
- USA lab
$79
PT-141 (Bremelanotide) is a synthetic melanocortin-receptor agonist reference material used in laboratory investigations of melanocortin-receptor activity and associated signaling pathways.
- Melanocortin-receptor binding research
- Receptor-mediated signaling studies
- In-vitro neuroendocrine-signaling models
SKU: AP-PT141-10MG
3 vial minimum per order — mix any products
Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Reconstitution ReferenceOptional — how strong is the mixed vial?
Mixing a powder vial with water? Fill in the fields — results update as you type.
Mixing 10 mg of peptide into 2 mL of water makes a 5 mg/mL solution. Each 0.1 mL contains 0.5 mg.
Reference for in-vitro laboratory handling only. Outputs describe the physical properties of the reconstituted vial (concentration and mass drawn) — they are not dosing guidance, administration instructions, or medical advice. Verify all measurements independently.
The science behind PT-141
A structured overview of the published literature surrounding PT-141 (Bremelanotide) as a melanocortin-receptor research peptide.
PT-141 (Bremelanotide) is a synthetic cyclic peptide analog of α-melanocyte-stimulating hormone (α-MSH) that acts as a melanocortin-receptor agonist. It is studied as a reference material for melanocortin-signaling research.
Derived from melanotan research, PT-141 is referenced in neuroendocrine and receptor-pharmacology literature focused on the melanocortin system.
The material supplied here is a laboratory reference standard, and the summaries below describe only findings reported in published research.
PT-141 was developed from research on melanotan-II and the melanocortin peptide family, isolating a metabolite with activity at melanocortin receptors, notably MC4R.
The literature includes preclinical receptor-pharmacology and neuroendocrine models, alongside clinical research on melanocortin-system signaling.
The primary mechanism studied is agonism at melanocortin receptors (particularly MC4R and MC3R), reported to activate cAMP-dependent signaling in receptor-expressing cells.
Researchers examine downstream neuroendocrine signaling in preclinical central-nervous-system models, framed as mechanistic laboratory observations.
Melanocortin-receptor assays
Used as a reference agonist in MC3R/MC4R activation studies.
Receptor signaling
Examined in cAMP-dependent signaling models.
Neuroendocrine research
Studied in preclinical central-signaling systems.
Comparative pharmacology
Referenced alongside other melanocortin analogs.
What is PT-141?
A synthetic cyclic melanocortin-receptor agonist peptide (Bremelanotide) supplied as a laboratory reference material for melanocortin-signaling research.
What kind of research references PT-141?
Receptor-pharmacology and neuroendocrine models of melanocortin-receptor activation.
Is PT-141 approved for human or veterinary use?
No. PT-141 is not approved by the FDA or any regulatory authority for human or animal use. It is sold exclusively for in-vitro and laboratory research and is not for consumption.
How is the reference material characterized?
Each released lot is supplied as a lyophilized powder with a lot-specific certificate of analysis reporting HPLC purity of ≥ 99%. The certificate is tied to the specific released lot.
How should the compound be stored?
Lyophilized material is typically stored at -20°C, protected from light and moisture. Handling should follow standard laboratory practice for peptide reference materials. We do not provide reconstitution, dosing, or administration guidance.
- Molinoff PB, et al. PT-141: a melanocortin agonist. Ann N Y Acad Sci (2003).
- Melanocortin-receptor pharmacology (review).
Links open a curated peer-reviewed search on PubMed. Allpointe Bio Research is not affiliated with the cited authors or publishers.
Research-Use Statement
The information above is provided for educational and scientific-reference purposes only and summarizes findings reported in the published preclinical and in-vitro literature. It is not medical advice and does not describe outcomes, benefits, or applications for humans or animals. PT-141 is supplied strictly as a laboratory reference material for in-vitro and research use only — it is not a drug or supplement, is not approved for human or veterinary use, and is not for consumption. Allpointe Bio Research does not provide clinical, dosing, reconstitution, or administration guidance.